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Anti-phospho-BCAR1(Tyr410)抗体

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产品名称: Anti-phospho-BCAR1(Tyr410)抗体
产品型号: 磷酸化乳腺癌抗雌**耐药蛋白1抗体
产品展商: 科研抗体
产品文档: 无相关文档

简单介绍

Anti-phospho-BCAR1(Tyr410)抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-phospho-BCAR1(Tyr410)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。


Anti-phospho-BCAR1(Tyr410)抗体  的详细介绍
Rabbit  Anti-phospho-BCAR1(Tyr410)
Cat. Number:
YB6224R
Quantity size:
0.1ml
Concentration:
Anti-phospho-BCAR1(Tyr410)抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
p130 represents one of several known substrates for v-Crk encoded p47. p130 Cas (for Crk-associated substrate) exhibits a high level of tyrosine phosphorylation and is tightly associated with v-Crk, suggesting a role in v-Crk-ted cell signaling. The molecular cloning of p130 Cas has shown it to represent a novel SH3 containing signaling molecule with a cluster of multiple putative SH2-binding motifs for v-Crk. Anti-phospho-BCAR1(Tyr410)抗体By immunoprecipitation analysis, p130 Cas has been shown to be highly phosphorylated at tyrosine residues subsequent to either v-Src p60 or v-Crk-ted transion and to form stable complexes with both of these transforming proteins. p130 Cas behaves as an extremely potent substrate for protein tyrosine kinases and has been reported to relocate from the cytoplasm to cell membrane upon tyrosine phosphorylation. One proposed model is that the SH2 domain of v-Crk functions to activate c-Src kinase, which in turn phosphorylates p130 Cas.
Also known as:
Anti-phospho-BCAR1(Tyr410)抗体BCAR1 (phospho Y410); BCAR1(phospho Y410); p-BCAR1(p-Tyr410); Breast cancer anti estrogen resistance 1 protein; BCAR 1; Bcar1; BCAR1_HUMAN; Breast cancer anti estrogen resistance 1; Breast cancer anti-estrogen resistance protein 1; CAS; Cas scaffolding protein family member 1; Crk associated substrate; Crk associated substrate p130Cas; CRK-associated substrate; CRKAS; P130CAS.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Horse, .
Immunogen: KLH conjugated Synthesised phosphopeptide derived from human BCAR1 around the phosphorylation site of Tyr410..
Predicted Molecular Weight: 93kDa.
Storage:
Shipped at 4℃,Anti-phospho-BCAR1(Tyr410)抗体 Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-phospho-BCAR1(Tyr410)抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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