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Anti-BARD1抗体

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产品名称: Anti-BARD1抗体
产品型号: 乳腺癌易感基因环状结构域蛋白抗体
产品展商: 科研抗体
产品文档: 无相关文档

简单介绍

Anti-BARD1抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-BARD1抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。


Anti-BARD1抗体  的详细介绍
Rabbit  Anti-BARD1
Cat. Number:
YB4291R
Quantity size:
0.1ml
Concentration:
Anti-BARD1抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
BRCA1 Associated RING Domain gene 1 (BARD1) interacts with the N terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, BARD1 shares homology with the 2 most conserved regions of BRCA1: Anti-BARD1抗体the N terminal RING motif and the C terminal BRCT domain. The RING motif is a cysteine rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. The BARD1 protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the ion of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. BARD1 may be the target of oncogenic mutations in breast or ovarian cancer. BARD1 also plays a role in ting apoptotic stress and p53 dependent.
Also known as:
Anti-BARD1抗体BARD-1; Bard1; Bard 1; BARD1_HUMAN; BRCA1 associated RING domain 1; BRCA1 associated RING domain gene 1; BRCA1 associated RING domain protein 1; BRCA1-associated RING domain protein 1.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Anti-BARD1抗体Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, .
Immunogen: KLH conjugated synthetic peptide derived from human BARD1.
Predicted Molecular Weight: 85kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-BARD1抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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