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Anti-phospho-B-Raf (Thr401)抗体

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产品名称: Anti-phospho-B-Raf (Thr401)抗体
产品型号: 磷酸化B-Raf抗体
产品展商: 科研抗体
产品文档: 无相关文档

简单介绍

Anti-phospho-B-Raf (Thr401)抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-phospho-B-Raf (Thr401)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。


Anti-phospho-B-Raf (Thr401)抗体  的详细介绍
Rabbit  Anti-phospho-B-Raf (Thr401)
Cat. Number:
YB5224R
Quantity size:
0.1ml
Concentration:
Anti-phospho-B-Raf (Thr401)抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The Raf kinases are important intertes in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-ted phosphorylation and activation of MEK (also known as MAP kinase kinase). Anti-phospho-B-Raf (Thr401)抗体Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.
Also known as:
Anti-phospho-B-Raf (Thr401)抗体B Raf (phospho T401); p-B Raf (phospho T401); 94 kDa B raf protein; B raf 1; B Raf proto oncogene serine threonine protein kinase; BRAF 1; Braf; BRAF1; cRmil; MGC126806; MGC138284; Murine sarcoma viral (v-raf) oncogene homolog B1; Murine sarcoma viral v raf oncogene homolog B1; p94; RAFB 1; RAFB1; v raf murine sarcoma viral oncogene homolog B1; FLJ95109; BRAF_HUMAN.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, .
Immunogen: Anti-phospho-B-Raf (Thr401)抗体KLH conjugated Synthesised phosphopeptide derived from human B-Raf around the phosphorylation site of Thr401.
Predicted Molecular Weight: 94kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-phospho-B-Raf (Thr401)抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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