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Anti-phospho-Bid (Ser61)抗体

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产品名称: Anti-phospho-Bid (Ser61)抗体
产品型号: 磷酸化BH3结构域凋亡诱导蛋白抗体
产品展商: 科研抗体
产品文档: 无相关文档

简单介绍

Anti-phospho-Bid (Ser61)抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-phospho-Bid (Ser61)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。


Anti-phospho-Bid (Ser61)抗体  的详细介绍
Rabbit  Anti-phospho-Bid (Ser61)
Cat. Number:
YB5231R
Quantity size:
0.1ml
Concentration:
Anti-phospho-Bid (Ser61)抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Bid, a BH3 domain containing proapoptotic Bcl2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase 8 in the Fas signaling pathway. Anti-phospho-Bid (Ser61)抗体Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In animal model studies, Bid deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.
Also known as:
Anti-phospho-Bid (Ser61)抗体Bid (phospho S61); p-Bid (phospho S61); BH3 interacting domain death agonist; p22 BID; BID;) BH3-interacting domain death agonist; AltName: BH3-interacting domain death agonist p15; BH3-interacting domain death agonist p13; p13 BID; BH3-interacting domain death agonist p11; p11 BID.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Mouse, .
Immunogen: Anti-phospho-Bid (Ser61)抗体KLH conjugated Synthesised phosphopeptide derived from mouse Bid around the phosphorylation site of Ser61.
Predicted Molecular Weight: 21kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-phospho-Bid (Ser61)抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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