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Anti-phospho-ARP3 (Ser418)抗体

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产品名称: Anti-phospho-ARP3 (Ser418)抗体
产品型号: 磷酸化细胞骨架肌动蛋白样蛋白3抗体
产品展商: 科研抗体
产品文档: 无相关文档

简单介绍

Anti-phospho-ARP3 (Ser418)抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-phospho-ARP3 (Ser418)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。


Anti-phospho-ARP3 (Ser418)抗体  的详细介绍
Rabbit  Anti-phospho-ARP3 (Ser418)
Cat. Number:
YB8999R
Quantity size:
0.1ml
Concentration:
Anti-phospho-ARP3 (Ser418)抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Actin polymerization is required for a variety of cell functions, including chemotaxis, cell migration, cell adhesion, and platelet activation. Cells trigger actin polymerization through either the de novo nucleation of filaments from monomeric actin, the severing of existing filaments to create uncapped barbed ends, or the uncapping existing barbed ends. The nucleation of actin is a rate-limiting and unfavorable reaction in actin polymerization and therefore requires the involvement of the Arp2/3 complex, which helps create new filaments and promotes the end-to-side cross-linking of actin filaments into the branching meshwork. The Arp2/3 complex consists of the actin-related proteins Arp2 and Arp3, and various other accessory proteins.Anti-phospho-ARP3 (Ser418)抗体 The Arp2/3 complex promotes actin nucleation by binding the pointed end of actin filaments, or by associating with the side of an existing filament, and nucleates growth in the barbed direction. In addition, the Arp2/3 complex also tes actin cytoskeletal outgrowths that are regulated by the Rho family of small GTPases. In response to GTP-binding Cdc42, the Arp2/3 complex binds the Cdc42 substrates, namely the WASP proteins, and initiates the ion of lamellipodia and filopodia.
Also known as:
Anti-phospho-ARP3 (Ser418)抗体ARP3 (phospho-Ser418); ARP3 (phospho S418); Actin-like protein 3; Actin-related protein 3; ACTR3; ARP3 actin-related protein 3 homolog; ARP3_HUMAN.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human,Anti-phospho-ARP3 (Ser418)抗体 Mouse, Rat, .
Immunogen: KLH conjugated synthetic peptide derived from human phospho-ARP3 (Ser418).
Predicted Molecular Weight: 47kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-phospho-ARP3 (Ser418)抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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