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Anti-phospho-AKT3 (Tyr473)抗体

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产品名称: Anti-phospho-AKT3 (Tyr473)抗体
产品型号: 磷酸化蛋白激酶B抗体
产品展商: 科研抗体
产品文档: 无相关文档

简单介绍

Anti-phospho-AKT3 (Tyr473)抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-phospho-AKT3 (Tyr473)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。


Anti-phospho-AKT3 (Tyr473)抗体  的详细介绍
Rabbit  Anti-phospho-AKT3 (Tyr473)
Cat. Number:
YB15963R
Quantity size:
0.1ml
Concentration:
Anti-phospho-AKT3 (Tyr473)抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase.Anti-phospho-AKT3 (Tyr473)抗体 In the developing nervous system AKT is a critical tor of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
Also known as:
Anti-phospho-AKT3 (Tyr473)抗体AKT3 (phospho Y473); p-AKT3 (phospho Y473); phospho-AKT1(Tyr474); phospho-AKT2 (Tyr475); AKT1(phospho Tyr474); AKT2 (phospho Tyr475); AKT3(phospho Tyr473); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; AKT 2; AKT2; AKT-2; AKT2_HUMAN; AKT 3; AKT3; AKT-3; AKT3_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PKB beta; PKB gamma; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, .
Immunogen:Anti-phospho-AKT3 (Tyr473)抗体 KLH conjugated synthesised phosphopeptide derived from human AKT3 around the phosphorylation site of Tyr473.
Predicted Molecular Weight: 57kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-phospho-AKT3 (Tyr473)抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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