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Anti-ATIC/PURH抗体

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产品名称: Anti-ATIC/PURH抗体
产品型号: AICAR甲酰基转移酶抗体
产品展商: 科研抗体
产品文档: 无相关文档

简单介绍

Anti-ATIC/PURH抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-ATIC/PURH抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。


Anti-ATIC/PURH抗体  的详细介绍
Rabbit  Anti-ATIC/PURH
Cat. Number:
YB12544R
Quantity size:
0.1ml
Concentration:
Anti-ATIC/PURH抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
The bifunctional purine biosynthesis protein ATIC (also designated PURH) contains AICAR transformylase and IMP cyclohydrolase activities. AICAR (5-aminoimidazole-4-carboxamide ribonucleotide) transformylase catalyzes the second to last step in purine biosynthesis, playing an important role in the production of nucleotides and IMP. Defects in the ATIC transformylase gene can cause AICA-rebsuria, also designated AICA-ribosiduria, an inborn error in purine biosynthesis that is neurologically cataclysmic. Anti-ATIC/PURH抗体Individuals with AICA-rebosuria accumulate AICA-riboside, also designated ZMP, and its derivatives in erythrocytes and fibroblasts. Patients also excrete very large amounts of AICA-riboside in the urine. Mental retardation, epilepsy, dysmorphic features and congenital blindness are all symptoms of this disease.
Also known as:
Anti-ATIC/PURH抗体AICAR transformylase; 5 aminoimidazole 4 carboxamide 1 beta D ribonucleotide transformylase/inosinicase; 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase; 5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; AICAR; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICARFT; AICARFT/IMPCHASE; ATIC; Bifunctional purine biosynthesis protein PURH; FLJ93545; IMP cyclohydrolase; IMP synthase; IMP synthetase; IMPCHASE; Inosinicase; OK/SW-cl.86; Phosphoribosylaminoimidazolecarboxamide formyltransferase; Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PUR9_HUMAN; PURH.
Specificity:
Rabbit Polyclonal IgG,Anti-ATIC/PURH抗体affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, .
Immunogen: KLH conjugated synthetic peptide derived from human ATIC/AICAR transformylase.
Predicted Molecular Weight: 65kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-ATIC/PURH抗体WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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