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Anti-phospho-APC (Ser2054)抗体

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产品名称: Anti-phospho-APC (Ser2054)抗体
产品型号: 磷酸化腺瘤样息肉抗体
产品展商: 科研抗体
产品文档: 无相关文档

简单介绍

Anti-phospho-APC (Ser2054)抗体供应商为您提供抗体的售前、售中、售后服务,现货供应,保证实验结果,无效可以免费退换,广泛应用于IHC、WB、 IF、IP、ELISA,质量保证,另外本公司生产经营各种单克隆抗体、多克隆抗体,标记二抗、**印迹常用试剂、**组化常用试剂,Anti-phospho-APC (Ser2054)抗体用于**组化实验,WB实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。


Anti-phospho-APC (Ser2054)抗体  的详细介绍
Rabbit  Anti-phospho-APC (Ser2054)
Cat. Number:
YB12481R
Quantity size:
0.1ml
Concentration:
Anti-phospho-APC (Ser2054)抗体1mg/ml   Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator.Anti-phospho-APC (Ser2054)抗体 APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a tor of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
Also known as:
Anti-phospho-APC (Ser2054)抗体APC (phospho S2054); p-APC (phospho S2054); Adenomatous Polyposis Coli; APC; CC1; DP2; DP2.5; DP3; FAP; FPC; GS; Protein APC.
Specificity:
Rabbit Polyclonal IgG, affinity purified by Protein A.
Reacts with: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, .
Immunogen: Anti-phospho-APC (Ser2054)抗体KLH conjugated synthesised phosphopeptide derived from human APC around the phosphorylation site of Ser2054.
Predicted Molecular Weight: 312kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-phospho-APC (Ser2054)抗体IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
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